Pirfenidone
Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3.
| Trivial name | S-7701, AMR-69 |
| Catalog Number | S2907 |
| Molecular Formula | C21H27N5O3 |
| CAS# | 53179-13-8 |
| Inchi | InChI=1S/C21H27N5O3/c1-21(2,28)17-9-4-13(10-22-17)16-11-23-19-20(25-16)26(18(27)12-24-19)14-5-7-15(29-3)8-6-14/h4,9-11,14-15,28H,5-8,12H2,1-3H3,(H,23,24)/t14-,15- |
| Inchi Key | UFKLYTOEMRFKAD-SHTZXODSSA-N |
| SMILES | CC(C)(C1=NC=C(C=C1)C2=CN=C3C(=N2)N(C(=O)CN3)C4CCC(CC4)OC)O |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/pirfenidone.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Pirfenidone-chemical-structure-s2907.jpg |