NU7026
NU7026 (LY293646) is a potent DNA-PK inhibitor with IC50 of 0.23 μM in cell-free assays, 60-fold selective for DNA-PK than PI3K and inactive against both ATM and ATR. NU7026 enhances G2/M cell arrest and apoptosis.
| Trivial name | LY293646 |
| Catalog Number | S2893 |
| Molecular Formula | C17H15NO3 |
| CAS# | 154447-35-5 |
| Inchi | InChI=1S/C17H15NO3/c19-15-11-16(18-7-9-20-10-8-18)21-17-13-4-2-1-3-12(13)5-6-14(15)17/h1-6,11H,7-10H2 |
| Inchi Key | KKTZALUTXUZPSN-UHFFFAOYSA-N |
| SMILES | C1COCCN1C2=CC(=O)C3=C(O2)C4=CC=CC=C4C=C3 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/nu7026.html |
| Additional Information | https://file.selleck.cn/downloads/struct/NU7026-chemical-structure-s2893.gif |