IKK-16
IKK-16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM in cell-free assays, respectively. IKK-16 also inhibits LRRK2 Ser935 phosphorylation in cells and LRRK2 kinase activity in vitro with IC50 of 50 nM.
| Trivial name | IKK Inhibitor VII |
| Catalog Number | S2882 |
| Molecular Formula | C17H17ClN2O5 |
| CAS# | 873225-46-8 |
| Inchi | InChI=1S/C17H17ClN2O5/c1-3-23-16(21)11(8-19)13-10-7-9(18)5-6-12(10)25-15(20)14(13)17(22)24-4-2/h5-7,11,13H,3-4,20H2,1-2H3 |
| Inchi Key | DXVKFBGVVRSOLI-UHFFFAOYSA-N |
| SMILES | CCOC(=O)C1=C(OC2=C(C1C(C#N)C(=O)OCC)C=C(C=C2)Cl)N |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/ikk-16.html |
| Additional Information | https://file.selleck.cn/downloads/struct/IKK-16-chemical-structure-s2882.jpg |