GW5074
GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted. GW5074 inhibits LK-induced apoptosis.
| Trivial name | N/A |
| Catalog Number | S2872 |
| Molecular Formula | C15H8Br2INO2 |
| CAS# | 220904-83-6 |
| Inchi | InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21) |
| Inchi Key | LMXYVLFTZRPNRV-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C=C1I)C(=CC3=CC(=C(C(=C3)Br)O)Br)C(=O)N2 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/gw5074.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gw5074-chemical-structure-s2872.gif |