GW5074
GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted. GW5074 inhibits LK-induced apoptosis.
| Trivial name | N/A |
| Catalog Number | S2872 |
| Molecular Formula | C21H29N6O5P |
| CAS# | 220904-83-6 |
| Inchi | InChI=1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24)/t15-,16+,33+/m1/s1 |
| Inchi Key | LDEKQSIMHVQZJK-CAQYMETFSA-N |
| SMILES | CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC3=CC=CC=C3 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/gw5074.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gw5074-chemical-structure-s2872.gif |