Carfilzomib (PR-171)

Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM in ANBL-6 cells, displayed preferential in vitro inhibitory potency against the ChT-L activity in the β5 subunit, but little or no effect on the PGPH and T-L activities. Carfilzomib activates prosurvival autophagy and induces cell apoptosis.

Price Not Available 5mg Carfilzomib (PR-171) Supplier Page

Trivial name	N/A
Catalog Number	S2853
Molecular Formula	C29H28N4O2
CAS#	868540-17-4
Inchi	InChI=1S/C29H28N4O2/c1-4-30-26(34)17-13-20-12-16-24-25(18-20)32-29(35)27(24)28(22-8-6-5-7-9-22)31-23-14-10-21(11-15-23)19-33(2)3/h5-12,14-16,18,31H,4,19H2,1-3H3,(H,30,34)(H,32,35)/b28-27-
Inchi Key	FLBNLJLONKAPLR-DQSJHHFOSA-N
SMILES	CCNC(=O)C#CC1=CC2=C(C=C1)C(=C(N2)O)C(=NC3=CC=C(C=C3)CN(C)C)C4=CC=CC=C4
Size	5mg
Supplier Page	http://www.selleckchem.com/products/carfilzomib-pr-171.html
Additional Information	https://file.selleck.cn/downloads/struct/carfilzomib-PR-171-chemical-structure-s2853.gif