TAE226 (NVP-TAE226)
TAE226 (NVP-TAE226) is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met. TAE226 (NVP-TAE226) induces apoptosis.
| Trivial name | N/A |
| Catalog Number | S2820 |
| Molecular Formula | C23H25ClN6O3 |
| CAS# | 761437-28-9 |
| Inchi | InChI=1S/C23H25ClN6O3/c1-25-22(31)16-5-3-4-6-18(16)27-21-17(24)14-26-23(29-21)28-19-8-7-15(13-20(19)32-2)30-9-11-33-12-10-30/h3-8,13-14H,9-12H2,1-2H3,(H,25,31)(H2,26,27,28,29) |
| Inchi Key | UYJNQQDJUOUFQJ-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCOCC4)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/nvp-tae226.html |
| Additional Information | https://file.selleck.cn/downloads/struct/NVP-TAE226-chemical-structure-s2820.gif |