TAE226 (NVP-TAE226)
TAE226 (NVP-TAE226) is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met. TAE226 (NVP-TAE226) induces apoptosis.
Trivial name | N/A |
Catalog Number | S2820 |
Molecular Formula | C20H15ClF3N5 |
CAS# | 761437-28-9 |
Inchi | InChI=1S/C20H15ClF3N5/c21-15-6-16-14(10-28-19(16)29-11-15)5-12-2-4-18(26-7-12)27-9-13-1-3-17(25-8-13)20(22,23)24/h1-4,6-8,10-11H,5,9H2,(H,26,27)(H,28,29) |
Inchi Key | JGWRKYUXBBNENE-UHFFFAOYSA-N |
SMILES | C1=CC(=NC=C1CC2=CNC3=C2C=C(C=N3)Cl)NCC4=CN=C(C=C4)C(F)(F)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/nvp-tae226.html |
Additional Information | https://file.selleck.cn/downloads/struct/NVP-TAE226-chemical-structure-s2820.gif |