Tacedinaline (CI994)
Tacedinaline (CI994, PD-123654, GOE-5549, Acetyldinaline) is a selective class I HDAC inhibitor with IC50 of 0.9, 0.9, 1.2, and >20 μM for human HDAC 1, 2, 3, and 8, respectively. Phase 3.
Trivial name | PD-123654, GOE-5549, Acetyldinaline |
Catalog Number | S2818 |
Molecular Formula | C20H15ClF3N5 |
CAS# | 112522-64-2 |
Inchi | InChI=1S/C20H15ClF3N5/c21-15-6-16-14(10-28-19(16)29-11-15)5-12-2-4-18(26-7-12)27-9-13-1-3-17(25-8-13)20(22,23)24/h1-4,6-8,10-11H,5,9H2,(H,26,27)(H,28,29) |
Inchi Key | JGWRKYUXBBNENE-UHFFFAOYSA-N |
SMILES | C1=CC(=NC=C1CC2=CNC3=C2C=C(C=N3)Cl)NCC4=CN=C(C=C4)C(F)(F)F |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/ci994-tacedinaline.html |
Additional Information | https://file.selleck.cn/downloads/struct/CI994-chemical-structure-s2818.gif |