LY364947
LY364947 (HTS 466284) is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM in a cell-free assay, shows 7-fold selectivity over TGFβR-II.
| Trivial name | HTS 466284 |
| Catalog Number | S2805 |
| Molecular Formula | C17H12N4 |
| CAS# | 396129-53-6 |
| Inchi | InChI=1S/C17H12N4/c1-2-6-15-13(5-1)12(8-10-19-15)14-11-20-21-17(14)16-7-3-4-9-18-16/h1-11H,(H,20,21) |
| Inchi Key | IBCXZJCWDGCXQT-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)C(=CC=N2)C3=C(NN=C3)C4=CC=CC=N4 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/ly364947.html |
| Additional Information | https://file.selleck.cn/downloads/struct/LY364947-chemical-structure-s2805.gif |