Galeterone
Galeterone (TOK-001) is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively, and is a potent inhibitor of human prostate tumor growth. Phase 2.
| Trivial name | TOK-001 |
| Catalog Number | S2803 |
| Molecular Formula | C31H38N6O2 |
| CAS# | 851983-85-2 |
| Inchi | InChI=1S/C31H38N6O2/c1-19(2)37-18-21(4)29-25(30(38)33-17-26-20(3)13-22(5)34-31(26)39)14-24(15-27(29)37)23-7-8-28(32-16-23)36-11-9-35(6)10-12-36/h7-8,13-16,18-19H,9-12,17H2,1-6H3,(H,33,38)(H,34,39) |
| Inchi Key | HRDQQHUKUIKFHT-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(C(=O)N1)CNC(=O)C2=C3C(=CN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C)C(C)C)C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/galeterone-tok-001.html |
| Additional Information | https://file.selleck.cn/downloads/struct/VN124-1-chemical-structure-s2803.gif |