Lonafarnib (SCH66336)

Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.

Price Not Available 10mM/1mL Lonafarnib (SCH66336) Supplier Page

Trivial name	N/A
Catalog Number	S2797
Molecular Formula	C23H28N2O2.2HCl
CAS#	193275-84-2
Inchi	InChI=1S/C23H28N2O2.2ClH/c26-23(27)20-8-6-18(7-9-20)16-25-12-10-17(11-13-25)15-24-22-14-21(22)19-4-2-1-3-5-19;;/h1-9,17,21-22,24H,10-16H2,(H,26,27);2*1H/t21-,22+;;/m0../s1
Inchi Key	QEKGSBZKRLHQSZ-VSIGASKDSA-N
SMILES	C1CN(CCC1CNC2CC2C3=CC=CC=C3)CC4=CC=C(C=C4)C(=O)O.Cl.Cl
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/lonafarnib-sch66336.html
Additional Information	https://file.selleck.cn/downloads/struct/Lonafarnib-chemical-structure-s2797.gif