GW4064
GW4064 is an agonist of farnesoid X receptor (FXR) with EC50 of 65 nM in CV1 cell line and displays no activity at other nuclear receptors at concentrations up to 1 μM. GW4064 stimulates autophagy in MCF-7 cells.
| Trivial name | N/A |
| Catalog Number | S2782 |
| Molecular Formula | C28H22Cl3NO4 |
| CAS# | 278779-30-9 |
| Inchi | InChI=1S/C28H22Cl3NO4/c1-16(2)27-21(26(32-36-27)25-22(29)7-4-8-23(25)30)15-35-20-12-11-18(24(31)14-20)10-9-17-5-3-6-19(13-17)28(33)34/h3-14,16H,15H2,1-2H3,(H,33,34)/b10-9+ |
| Inchi Key | BYTNEISLBIENSA-MDZDMXLPSA-N |
| SMILES | CC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC(=C(C=C3)C=CC4=CC(=CC=C4)C(=O)O)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/gw-4064.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GW-4064-chemical-structure-s2782.jpg |