GW4064
GW4064 is an agonist of farnesoid X receptor (FXR) with EC50 of 65 nM in CV1 cell line and displays no activity at other nuclear receptors at concentrations up to 1 μM. GW4064 stimulates autophagy in MCF-7 cells.
| Trivial name | N/A |
| Catalog Number | S2782 |
| Molecular Formula | C26H34O7 |
| CAS# | 278779-30-9 |
| Inchi | InChI=1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20-,23-,24 -,25+,26+/m1/s1 |
| Inchi Key | NGGMYCMLYOUNGM-CSDLUJIJSA-N |
| SMILES | CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/gw-4064.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GW-4064-chemical-structure-s2782.jpg |