Devimistat (CPI-613)
Devimistat (CPI-613), a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase in NCI-H460 cell line, disrupts tumor cell mitochondrial metabolism. CPI-613 induces apoptosis in pancreatic cancer cells. Phase 2.
Trivial name | N/A |
Catalog Number | S2776 |
Molecular Formula | C26H21N3O3 |
CAS# | 95809-78-2 |
Inchi | InChI=1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,27,30-31H,14-15H2 |
Inchi Key | YHIPILPTUVMWQT-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)CC2=NC(=CN3C2=NC(=C3O)CC4=CC=C(C=C4)O)C5=CC=C(C=C5)O |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/cpi-613.html |
Additional Information | https://file.selleck.cn/downloads/struct/CPI-613-chemical-structure-s2776.gif |