Canagliflozin (JNJ 28431754)

Canagliflozin (TA 7284, JNJ 28431754) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.

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Trivial name	TA 7284
Catalog Number	S2760
Molecular Formula	C24H25FO5S
CAS#	842133-18-0
Inchi	InChI=1S/C24H25FO5S/c1-13-2-3-15(24-23(29)22(28)21(27)19(12-26)30-24)10-16(13)11-18-8-9-20(31-18)14-4-6-17(25)7-5-14/h2-10,19,21-24,26-29H,11-12H2,1H3/t19-,21-,22+,23-,24+/m1/s1
Inchi Key	XTNGUQKDFGDXSJ-ZXGKGEBGSA-N
SMILES	CC1=C(C=C(C=C1)C2C(C(C(C(O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F
Size	10mg
Supplier Page	http://www.selleckchem.com/products/canagliflozin.html
Additional Information	https://file.selleck.cn/downloads/struct/Canagliflozin-chemical-structure-s2760.gif