Varlitinib
Varlitinib (ARRY334543) is a selective and potent ErbB1(EGFR) and ErbB2(HER2) inhibitor with IC50 of 7 nM and 2 nM, respectively. Phase 2.
| Trivial name | ARRY334543 |
| Catalog Number | S2755 |
| Molecular Formula | C29H27F5N2O6S |
| CAS# | 845272-21-1 |
| Inchi | InChI=1S/C29H27F5N2O6S/c1-35(43(41,42)28-26(33)24(31)23(30)25(32)27(28)34)15-22(38)36(19-11-12-20(29(39)40)21(37)13-19)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h7-13,17,37H,2-6,14-15H2,1H3,(H,39,40) |
| Inchi Key | WNVSFFVDMUSXSX-UHFFFAOYSA-N |
| SMILES | CN(CC(=O)N(CC1=CC=C(C=C1)C2CCCCC2)C3=CC(=C(C=C3)C(=O)O)O)S(=O)(=O)C4=C(C(=C(C(=C4F)F)F)F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/arry334543.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ARRY-334543-chemical-structure-s2755.gif |