AZ 628
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM in cell-free assays, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc. AZ628 induces apoptosis.
| Trivial name | N/A |
| Catalog Number | S2746 |
| Molecular Formula | C16H19N3S.2CH4O3S |
| CAS# | 878739-06-1 |
| Inchi | InChI=1S/C16H19N3S.2CH4O3S/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;2*1-5(2,3)4/h5-10,17H,1-4H3;2*1H3,(H,2,3,4) |
| Inchi Key | SPCMQFLNOVTUBM-UHFFFAOYSA-N |
| SMILES | CN(C)C1=CC2=C(C=C1)NC3=C(S2)C=C(C=C3)N(C)C.CS(=O)(=O)O.CS(=O)(=O)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/az628.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AZ628-chemical-structure-s2746.gif |