MK-8776 (SCH 900776)
MK-8776 (SCH 900776) is a selective Chk1 inhibitor with IC50 of 3 nM in a cell-free assay. It shows 500-fold selectivity against Chk2. Phase 2.
| Trivial name | N/A |
| Catalog Number | S2735 |
| Molecular Formula | C18H13N3OS2 |
| CAS# | 891494-63-6 |
| Inchi | InChI=1S/C18H13N3OS2/c22-17-16(24-18(21-17)20-11-14-4-2-8-23-14)10-12-5-6-15-13(9-12)3-1-7-19-15/h1-10H,11H2,(H,20,21,22)/b16-10- |
| Inchi Key | XOLMRFUGOINFDQ-YBEGLDIGSA-N |
| SMILES | C1=CC2=C(C=CC(=C2)C=C3C(=O)NC(=NCC4=CC=CS4)S3)N=C1 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/sch-900776.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SCH-900776-chemical-structure-s2735.gif |