AZ 3146
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit.
Trivial name | N/A |
Catalog Number | S2731 |
Molecular Formula | C18H13N3OS2 |
CAS# | 1124329-14-1 |
Inchi | InChI=1S/C18H13N3OS2/c22-17-16(24-18(21-17)20-11-14-4-2-8-23-14)10-12-5-6-15-13(9-12)3-1-7-19-15/h1-10H,11H2,(H,20,21,22)/b16-10- |
Inchi Key | XOLMRFUGOINFDQ-YBEGLDIGSA-N |
SMILES | C1=CC2=C(C=CC(=C2)C=C3C(=O)NC(=NCC4=CC=CS4)S3)N=C1 |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/az-3146.html |
Additional Information | https://file.selleck.cn/downloads/struct/az-3146-chemical-structure-s2731.gif |