SB415286
SB415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β. SB415286 causes MM cell growth arrest and apoptosis.
Trivial name | N/A |
Catalog Number | S2729 |
Molecular Formula | C18H12N4OS |
CAS# | 264218-23-7 |
Inchi | InChI=1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24) |
Inchi Key | GSRTWXVBHGOUBU-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4 |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/sb-415286.html |
Additional Information | https://file.selleck.cn/downloads/struct/SB415286-chemical-structure-s2729.gif |