AMG-900
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2. Phase 1.
| Trivial name | N/A |
| Catalog Number | S2719 |
| Molecular Formula | C11H8Br2N2O2 |
| CAS# | 945595-80-2 |
| Inchi | InChI=1S/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)/b8-6- |
| Inchi Key | UVSVTDVJQAJIFG-VURMDHGXSA-N |
| SMILES | CC(=C(C#N)C(=O)NC1=C(C=CC(=C1)Br)Br)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/amg-900.html |
| Additional Information | https://file.selleck.cn/downloads/struct/amg-900-chemical-structure-s2719.gif |