LY411575
LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch cleavage with IC50 of 0.39 nM in APP or NΔE expressing HEK293 cells. LY411575 induces apoptosis.
| Trivial name | N/A |
| Catalog Number | S2714 |
| Molecular Formula | C9H8N2O2 |
| CAS# | 209984-57-6 |
| Inchi | InChI=1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4,12H,1H3,(H,10,11,13) |
| Inchi Key | YJDAOHJWLUNFLX-UHFFFAOYSA-N |
| SMILES | CC1=NC2=C(C=CC=C2O)C(=O)N1 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ly-411575.html |
| Additional Information | https://file.selleck.cn/downloads/struct/LY-411575-chemical-structure-s2714.gif |