LY411575
LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch cleavage with IC50 of 0.39 nM in APP or NΔE expressing HEK293 cells. LY411575 induces apoptosis.
| Trivial name | N/A |
| Catalog Number | S2714 |
| Molecular Formula | C16H16N2O3 |
| CAS# | 209984-57-6 |
| Inchi | InChI=1S/C16H16N2O3/c19-15(17-10-9-12-5-2-1-3-6-12)13-7-4-8-14(11-13)16(20)18-21/h1-8,11,21H,9-10H2,(H,17,19)(H,18,20) |
| Inchi Key | FIHKWEQJEDRIFS-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CCNC(=O)C2=CC(=CC=C2)C(=O)NO |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/ly-411575.html |
| Additional Information | https://file.selleck.cn/downloads/struct/LY-411575-chemical-structure-s2714.gif |