NSC 207895
NSC 207895 (XI-006) suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.
| Trivial name | XI-006 |
| Catalog Number | S2678 |
| Molecular Formula | C24H25F2N3O4 |
| CAS# | 58131-57-0 |
| Inchi | InChI=1S/C24H25F2N3O4/c1-14(27-18-11-16(25)10-17(26)12-18)19-8-15(24(31)28(2)3)9-20-21(30)13-22(33-23(19)20)29-4-6-32-7-5-29/h8-14,27H,4-7H2,1-3H3/t14-/m1/s1 |
| Inchi Key | LMJFJIDLEAWOQJ-CQSZACIVSA-N |
| SMILES | CC(C1=CC(=CC2=C1OC(=CC2=O)N3CCOCC3)C(=O)N(C)C)NC4=CC(=CC(=C4)F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/nsc-207895-xi-006.html |
| Additional Information | https://file.selleck.cn/downloads/struct/NSC-207895-chemical-structure-s2678.gif |