ICG-001

ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300. ICG-001 induces apoptosis.

Price Not Available 10mM/1mL ICG-001 Supplier Page

Catalog Number	S2662
Molecular Formula	C24H20N4O4S
CAS#	780757-88-2 (relative stereochemistry); 847591-62-2 (absolute stereochemistry)
Inchi	InChI=1S/C24H20N4O4S/c1-30-24-26-23(16-7-12-20-21(13-16)32-15-31-20)28(27-24)18-10-8-17(9-11-18)25-22(29)14-33-19-5-3-2-4-6-19/h2-13H,14-15H2,1H3,(H,25,29)
Inchi Key	QPGYAMIHXLCFTJ-UHFFFAOYSA-N
SMILES	COC1=NN(C(=N1)C2=CC3=C(C=C2)OCO3)C4=CC=C(C=C4)NC(=O)CSC5=CC=CC=C5
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/icg-001.html
Additional Information	https://file.selleck.cn/downloads/struct/icg001-chemical-structure-s2662.gif