ICG-001
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300. ICG-001 induces apoptosis.
| Catalog Number | S2662 |
| Molecular Formula | C22H30O2S |
| CAS# | 780757-88-2 (relative stereochemistry); 847591-62-2 (absolute stereochemistry) |
| Inchi | InChI=1S/C22H30O2S/c1-17(2)9-7-10-18(3)11-8-12-19(4)15-16-25-21-14-6-5-13-20(21)22(23)24/h5-6,9,11,13-15H,7-8,10,12,16H2,1-4H3,(H,23,24)/b18-11+,19-15+ |
| Inchi Key | WUILNKCFCLNXOK-CFBAGHHKSA-N |
| SMILES | CC(=CCCC(=CCCC(=CCSC1=CC=CC=C1C(=O)O)C)C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/icg-001.html |
| Additional Information | https://file.selleck.cn/downloads/struct/icg001-chemical-structure-s2662.gif |