Omipalisib (GSK2126458)

Omipalisib (GSK2126458, GSK458) is a highly selective and potent inhibitor of p110α/β/δ/γ, mTORC1/2 with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Omipalisib induces autophagy. Phase 1.

Price Not Available 5mg Omipalisib (GSK2126458) Supplier Page

Trivial name	GSK458
Catalog Number	S2658
Molecular Formula	C19H21ClF3N5O2
CAS#	1086062-66-9
Inchi	InChI=1S/C19H21ClF3N5O2/c1-12-11-30-5-4-26(12)16-7-17(29)27-3-2-15(19(21,22)23)28(18(27)25-16)10-13-6-14(20)9-24-8-13/h6-9,12,15H,2-5,10-11H2,1H3/t12-,15+/m1/s1
Inchi Key	SPDQRCUBFSRAFI-DOMZBBRYSA-N
SMILES	CC1COCCN1C2=CC(=O)N3CCC(N(C3=N2)CC4=CC(=CN=C4)Cl)C(F)(F)F
Size	5mg
Supplier Page	http://www.selleckchem.com/products/gsk2126458.html
Additional Information	https://file.selleck.cn/downloads/struct/GSK2126458-chemical-structure-s2658.gif