PF-04929113 (SNX-5422)
PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC50 of 37 nM. Phase 1/2.
| Trivial name | N/A |
| Catalog Number | S2656 |
| Molecular Formula | C19H20ClN3O5S |
| CAS# | 908115-27-5 |
| Inchi | InChI=1S/C19H20ClN3O5S/c1-13(17-12-15(20)5-6-18(17)24)21-22-19(25)14-3-2-4-16(11-14)29(26,27)23-7-9-28-10-8-23/h2-6,11-12,24H,7-10H2,1H3,(H,22,25)/b21-13+ |
| Inchi Key | NKUDGJUBIVEDTF-FYJGNVAPSA-N |
| SMILES | CC(=NNC(=O)C1=CC(=CC=C1)S(=O)(=O)N2CCOCC2)C3=C(C=CC(=C3)Cl)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pf-04929113.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PF-04929113-SNX-5422-chemical-structure-s2656.gif |