PF-04929113 (SNX-5422)
PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC50 of 37 nM. Phase 1/2.
| Trivial name | N/A |
| Catalog Number | S2656 |
| Molecular Formula | C25H30F3N5O4 |
| CAS# | 908115-27-5 |
| Inchi | InChI=1S/C25H30F3N5O4/c1-24(2)10-18-21(19(34)11-24)22(25(26,27)28)32-33(18)14-5-8-16(23(30)36)17(9-14)31-13-3-6-15(7-4-13)37-20(35)12-29/h5,8-9,13,15,31H,3-4,6-7,10-12,29H2,1-2H3,(H2,30,36)/t13-,15- |
| Inchi Key | AVDSOVJPJZVBTC-CTYIDZIISA-N |
| SMILES | CC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)OC(=O)CN)C(F)(F)F)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pf-04929113.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PF-04929113-SNX-5422-chemical-structure-s2656.gif |