SNX-2112
SNX-2112 selectively binds to the ATP pocket of HSP90α and HSP90β with Ka of 30 nM and 30 nM, uniformly more potent than 17-AAG.
| Trivial name | PF-04928473 |
| Catalog Number | S2639 |
| Molecular Formula | C23H27F3N4O3 |
| CAS# | 908112-43-6 |
| Inchi | InChI=1S/C23H27F3N4O3/c1-22(2)10-17-19(18(32)11-22)20(23(24,25)26)29-30(17)13-5-8-15(21(27)33)16(9-13)28-12-3-6-14(31)7-4-12/h5,8-9,12,14,28,31H,3-4,6-7,10-11H2,1-2H3,(H2,27,33)/t12-,14- |
| Inchi Key | ZFVRYNYOPQZKDG-MQMHXKEQSA-N |
| SMILES | CC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)O)C(F)(F)F)C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/snx-2112.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SNX-2112-chemical-structure-s2639.gif |