Fostamatinib (R788)
Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.
Trivial name | N/A |
Catalog Number | S2625 |
Molecular Formula | C26H24F3N7O3S |
CAS# | 901119-35-5 |
Inchi | InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-9-5-6-17(14-20)15-22(37)31-21-12-11-18(33-34-21)7-1-2-10-24-35-36-25(40-24)32-23(38)16-19-8-3-4-13-30-19/h3-6,8-9,11-14H,1-2,7,10,15-16H2,(H,31,34,37)(H,32,36 ,38) |
Inchi Key | PRAAPINBUWJLGA-UHFFFAOYSA-N |
SMILES | C1=CC=NC(=C1)CC(=O)NC2=NN=C(S2)CCCCC3=NN=C(C=C3)NC(=O)CC4=CC(=CC=C4)OC(F)(F)F |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/R7935788-Fostamatinib.html |
Additional Information | https://file.selleck.cn/downloads/struct/R788-chemical-structure-s2625.gif |