Rosiglitazone maleate
Rosiglitazone maleate, a member of the thiazolidinedione class of antihyperglycaemic agents, is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ (PPAR-γ) with IC50 of 42 nM. Rosiglitazone maleate also modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.
| Trivial name | BRL-49653C, BRL-49653 |
| Catalog Number | S2505 |
| Molecular Formula | C23H29ClN4O2S |
| CAS# | 155141-29-0 |
| Inchi | InChI=1S/C23H29ClN4O2S/c1-14-19(11-16(24)12-25-14)26-13-18-8-9-21(31-18)23(30)28-20(10-15-4-2-3-5-15)22(29)27-17-6-7-17/h8-9,11-12,15,17,20,26H,2-7,10,13H2,1H3,(H,27,29)(H,28,30)/t20-/m0/s1 |
| Inchi Key | IVDUVEGCMXCMSO-FQEVSTJZSA-N |
| SMILES | CC1=C(C=C(C=N1)Cl)NCC2=CC=C(S2)C(=O)NC(CC3CCCC3)C(=O)NC4CC4 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Rosiglitazone-maleate.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Rosiglitazone-maleate-chemical-structure-S2505.gif |