Imatinib
Imatinib is a multi-target inhibitor of tyrosine kinase with inhibition for v-Abl, c-Kit and PDGFR, IC50 values are 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib (STI571) induces autophagy.
| Trivial name | STI571, CGP-57148B |
| Catalog Number | S2475 |
| Molecular Formula | C16H14FIN4O3 |
| CAS# | 152459-95-5 |
| Inchi | InChI=1S/C16H14FIN4O3/c17-13-7-10(18)1-4-14(13)20-15-12(16(24)21-25-6-5-23)3-2-11-8-19-9-22(11)15/h1-4,7-9,20,23H,5-6H2,(H,21,24) |
| Inchi Key | RFWVETIZUQEJEF-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C=C1I)F)NC2=C(C=CC3=CN=CN32)C(=O)NOCCO |
| Size | 250mg |
| Supplier Page | http://www.selleckchem.com/products/Imatinib(STI571).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Imatinib-Gleevec-chemical-structure-S2475.gif |