Imatinib
Imatinib is a multi-target inhibitor of tyrosine kinase with inhibition for v-Abl, c-Kit and PDGFR, IC50 values are 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib (STI571) induces autophagy.
| Trivial name | STI571, CGP-57148B |
| Catalog Number | S2475 |
| Molecular Formula | C29H31N7O |
| CAS# | 152459-95-5 |
| Inchi | InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34) |
| Inchi Key | KTUFNOKKBVMGRW-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5 |
| Size | 250mg |
| Supplier Page | http://www.selleckchem.com/products/Imatinib(STI571).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Imatinib-Gleevec-chemical-structure-S2475.gif |