Buparlisib (BKM120)

Buparlisib (BKM120, NVP-BKM120) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Buparlisib induces apoptosis. Phase 2.

Price Not Available 5mg Buparlisib (BKM120) Supplier Page

Trivial name	NVP-BKM120
Catalog Number	S2247
Molecular Formula	C20H37N3O4
CAS#	944396-07-0
Inchi	InChI=1S/C20H37N3O4/c1-7-8-9-16(12-24)22-19(26)18(11-14(4)5)23-20(27)17(10-13(2)3)21-15(6)25/h12-14,16-18H,7-11H2,1-6H3,(H,21,25)(H,22,26)(H,23,27)/t16-,17-,18-/m0/s1
Inchi Key	FMYKJLXRRQTBOR-BZSNNMDCSA-N
SMILES	CCCCC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C
Size	5mg
Supplier Page	http://www.selleckchem.com/products/BKM-120.html
Additional Information	https://file.selleck.cn/downloads/struct/s2247-buparlisib-bkm120-chemical-structure.png