Degrasyn (WP1130)
Degrasyn (WP1130) is a selective deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor and also suppresses Bcr/Abl, also a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT). Degrasyn (WP1130) induces apoptosis and blocks autophagy.
| Trivial name | N/A |
| Catalog Number | S2243 |
| Molecular Formula | C19H18BrN3O |
| CAS# | 856243-80-6 |
| Inchi | InChI=1S/C19H18BrN3O/c1-2-7-17(14-8-4-3-5-9-14)23-19(24)15(13-21)12-16-10-6-11-18(20)22-16/h3-6,8-12,17H,2,7H2,1H3,(H,23,24)/b15-12+/t17-/m0/s1 |
| Inchi Key | LIDOPKHSVQTSJY-VMEIHUARSA-N |
| SMILES | CCCC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/WP1130.html |
| Additional Information | https://file.selleck.cn/downloads/struct/WP1130-chemical-structure-S2243.gif |