Idelalisib (CAL-101)

Idelalisib (CAL-101) is a selective p110δ inhibitor with IC50 of 2.5 nM in cell-free assays; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR. Idelalisib also stimulates autophagy.

Price Not Available 50mg Idelalisib (CAL-101) Supplier Page

Trivial name	GS-1101
Catalog Number	S2226
Molecular Formula	C17H20ClF4N7O
CAS#	870281-82-6
Inchi	InChI=1S/C17H20ClF4N7O/c1-23-15-10(17(20,21)22)4-24-16(27-15)26-12-5-25-29(14(12)18)13-2-3-28(6-11(13)19)9-7-30-8-9/h4-5,9,11,13H,2-3,6-8H2,1H3,(H2,23,24,26,27)/t11-,13-/m0/s1
Inchi Key	PUXPEQJKNAWNQA-AAEUAGOBSA-N
SMILES	CNC1=NC(=NC=C1C(F)(F)F)NC2=C(N(N=C2)C3CCN(CC3F)C4COC4)Cl
Size	50mg
Supplier Page	http://www.selleckchem.com/products/CAL-101.html
Additional Information	https://file.selleck.cn/downloads/struct/CAL-101-chemical-structure-S2226.gif