R406

R406(R406 besylate) is a potent Syk inhibitor with IC50 of 41 nM in cell-free assays, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. R406 induces apoptosis. Phase 1.

Price Not Available 5mg R406 Supplier Page
Trivial name R406 besylate
Catalog Number S2194
Molecular Formula C22H23FN6O5.C6H6O3S
CAS# 841290-81-1
Inchi InChI=1S/C22H23FN6O5.C6H6O3S/c1-22(2)20(30)28-19-13(34-22)6-7-16(27-19)26-18-12(23)10-24-21(29-18)25-11-8-14(31-3)17(33-5)15(9-11)32-4;7-10(8,9)6-4-2-1-3-5-6/h6-10H,1-5H3,(H3,24,25,26,27,28,29,30);1-5 H,(H,7,8,9)
Inchi Key UXDRJPYSTZHIOE-UHFFFAOYSA-N
SMILES CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)O
Size 5mg
Supplier Page http://www.selleckchem.com/products/R406.html
Additional Information https://file.selleck.cn/downloads/struct/R406-chemical-structure-S2194.gif