GSK461364
GSK461364 (GSK461364A) inhibits purified Plk1 with Ki of 2.2 nM in a cell-free assay. It is more than 1000-fold selective against Plk2/3.
| Trivial name | GSK461364A |
| Catalog Number | S2193 |
| Molecular Formula | C29H27F5N2O5S |
| CAS# | 929095-18-1 |
| Inchi | InChI=1S/C29H27F5N2O5S/c1-35(42(40,41)28-26(33)24(31)23(30)25(32)27(28)34)16-22(37)36(21-13-11-20(12-14-21)29(38)39)15-17-7-9-19(10-8-17)18-5-3-2-4-6-18/h7-14,18H,2-6,15-16H2,1H3,(H,38,39) |
| Inchi Key | VFPYGNNOSJWBHF-UHFFFAOYSA-N |
| SMILES | CN(CC(=O)N(CC1=CC=C(C=C1)C2CCCCC2)C3=CC=C(C=C3)C(=O)O)S(=O)(=O)C4=C(C(=C(C(=C4F)F)F)F)F |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/GSK461364.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GSK-461364-chemical-structure-S2193.gif |