SB505124
SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM in cell-free assays, respectively, also inhibits ALK7, but does not inhibit ALK1, 2, 3, or 6.
Trivial name | N/A |
Catalog Number | S2186 |
Molecular Formula | C22H15Br2N3O4 |
CAS# | 694433-59-5 |
Inchi | InChI=1S/C22H15Br2N3O4/c23-17-10-14(11-18(24)19(17)28)20-26-22(31-27-20)21(29)25-12-13-6-8-16(9-7-13)30-15-4-2-1-3-5-15/h1-11,28H,12H2,(H,25,29) |
Inchi Key | DSFNLJXHXBIKDS-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)OC2=CC=C(C=C2)CNC(=O)C3=NC(=NO3)C4=CC(=C(C(=C4)Br)O)Br |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/sb-505124.html |
Additional Information | https://file.selleck.cn/downloads/struct/SB505124-chemical-structure-s2186.gif |