Infigratinib (BGJ398)

Infigratinib (BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM in cell-free assays, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2.

Price Not Available 25mg Infigratinib (BGJ398) Supplier Page

Trivial name	NVP-BGJ398
Catalog Number	S2183
Molecular Formula	C25H21F3N4O3S
CAS#	872511-34-7
Inchi	InChI=1S/C25H21F3N4O3S/c26-25(27,28)22-31-20(32-35-22)17-7-4-8-18(13-17)21(33)29-15-24(9-11-34-12-10-24)23-30-19(14-36-23)16-5-2-1-3-6-16/h1-8,13-14H,9-12,15H2,(H,29,33)
Inchi Key	HORXBWNTEDOVKN-UHFFFAOYSA-N
SMILES	C1COCCC1(CNC(=O)C2=CC=CC(=C2)C3=NOC(=N3)C(F)(F)F)C4=NC(=CS4)C5=CC=CC=C5
Size	25mg
Supplier Page	http://www.selleckchem.com/products/bgj398-nvp-bgj398.html
Additional Information	https://file.selleck.cn/downloads/struct/BGJ398-chemical-structure-s2183.gif