AG-14361
AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM in a cell-free assay. It is at least 1000-fold more potent than the benzamides.
| Trivial name | N/A |
| Catalog Number | S2178 |
| Molecular Formula | C26H28N8O |
| CAS# | 328543-09-5 |
| Inchi | InChI=1S/C26H28N8O/c1-16-23-24(31-26(29-16)30-19-14-28-34(15-19)20-8-10-27-11-9-20)32(2)22-13-18-7-5-4-6-17(18)12-21(22)25(35)33(23)3/h4-7,12-15,20,27H,8-11H2,1-3H3,(H,29,30,31) |
| Inchi Key | CHSDJDLAKKAWCI-UHFFFAOYSA-N |
| SMILES | CC1=C2C(=NC(=N1)NC3=CN(N=C3)C4CCNCC4)N(C5=CC6=CC=CC=C6C=C5C(=O)N2C)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/AG14361.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AG14361-chemical-structure-S2178.gif |