Givinostat hydrochloride monohydrate

Givinostat (ITF2357) is a potent HDAC inhibitor for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM in cell-free assays. Phase 2.

Trivial name Givinostat (ITF2357)
Catalog Number S2170
Molecular Formula C25H23N3O4S
CAS# 732302-99-7
Inchi InChI=1S/C25H23N3O4S/c1-17-5-11-22(12-6-17)33(30,31)16-23-18(2)32-25(28-23)21-9-7-20(8-10-21)24(29)27-15-19-4-3-13-26-14-19/h3-14H,15-16H2,1-2H3,(H,27,29)
Inchi Key DLFCEZOMHBPDGI-UHFFFAOYSA-N
SMILES CC1=CC=C(C=C1)S(=O)(=O)CC2=C(OC(=N2)C3=CC=C(C=C3)C(=O)NCC4=CN=CC=C4)C
Size 10mM/1mL
Supplier Page http://www.selleckchem.com/products/ITF2357(Givinostat).html
Additional Information https://file.selleck.cn/downloads/struct/ITF2357-Givinostat-chemical-structure-S2170.gif