KW-2449
KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 with IC50 of 6.6 nM, modestly potent to FGFR1, Bcr-Abl and Aurora A; little effect on PDGFRβ, IGF-1R, EGFR. Phase 1.
| Trivial name | N/A |
| Catalog Number | S2158 |
| Molecular Formula | C20H20N4O |
| CAS# | 1000669-72-6 |
| Inchi | InChI=1S/C20H20N4O/c25-20(24-13-11-21-12-14-24)16-8-5-15(6-9-16)7-10-19-17-3-1-2-4-18(17)22-23-19/h1-10,21H,11-14H2,(H,22,23)/b10-7+ |
| Inchi Key | YYLKKYCXAOBSRM-JXMROGBWSA-N |
| SMILES | C1CN(CCN1)C(=O)C2=CC=C(C=C2)C=CC3=NNC4=CC=CC=C43 |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/KW-2449.html |
| Additional Information | https://file.selleck.cn/downloads/struct/KW-2449-chemical-structure-S2158.gif |