Roflumilast
Roflumilast is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM in a cell-free assay.
| Trivial name | APTA 2217, B9302-107, BY 217, BYK 20869 |
| Catalog Number | S2131 |
| Molecular Formula | C17H14Cl2F2N2O3 |
| CAS# | 162401-32-3 |
| Inchi | InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24) |
| Inchi Key | MNDBXUUTURYVHR-UHFFFAOYSA-N |
| SMILES | C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Roflumilast(Daxas).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Roflumilast-Daxas-chemical-structure-S2131.gif |