Roflumilast
Roflumilast is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM in a cell-free assay.
| Trivial name | APTA 2217, B9302-107, BY 217, BYK 20869 |
| Catalog Number | S2131 |
| Molecular Formula | C28 H33 N7 O2 |
| CAS# | 162401-32-3 |
| Inchi | InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32) |
| Inchi Key | DUYJMQONPNNFPI-UHFFFAOYSA-N |
| SMILES | CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Roflumilast(Daxas).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Roflumilast-Daxas-chemical-structure-S2131.gif |