Lapatinib
Lapatinib, used in the form of Lapatinib Ditosylate, is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. Lapatinib induces ferroptosis and autophagic cell death.
| Trivial name | GSK572016, GW2016 |
| Catalog Number | S2111 |
| Molecular Formula | C29H26ClFN4O4S |
| CAS# | 231277-92-2 |
| Inchi | InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35) |
| Inchi Key | BCFGMOOMADDAQU-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/lapatinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Lapatinib-chemical-structure-s2111.gif |