Lovastatin
Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, used for lowering cholesterol (hypolipidemic agent). Lovastatin triggers autophagy.
| Trivial name | Mevinolin, MK-803 |
| Catalog Number | S2061 |
| Molecular Formula | C24H36O5 |
| CAS# | 75330-75-5 |
| Inchi | InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1 |
| Inchi Key | PCZOHLXUXFIOCF-BXMDZJJMSA-N |
| SMILES | CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/lovastatin-mevacor.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s2061-lovastatin-mk-803-chemical-structure.png |