Maraviroc
Maraviroc is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM in cell-free assays, respectively. Maraviroc is used in the treatment of HIV infection.
Trivial name | UK-427857 |
Catalog Number | S2003 |
Molecular Formula | C25H24N4O2 |
CAS# | 376348-65-1 |
Inchi | InChI=1S/C25H24N4O2/c1-28(2)12-7-13-29-15-19(17-9-4-6-11-21(17)29)23-22(24(30)27-25(23)31)18-14-26-20-10-5-3-8-16(18)20/h3-6,8-11,14-15,26H,7,12-13H2,1-2H3,(H,27,30,31) |
Inchi Key | QMGUOJYZJKLOLH-UHFFFAOYSA-N |
SMILES | CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54 |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/Maraviroc.html |
Additional Information | https://file.selleck.cn/downloads/struct/Maraviroc-chemical-structure-S2003.gif |