Vadimezan (DMXAA)

Vadimezan (DMXAA) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM in cell-free assays, respectively. DMXAA (Vadimezan) is also a STING agonist with potential antineoplastic activity. DMXAA (Vadimezan) potently induces IFN-β but relatively low TNF-α expression in vitro. DMXAA (Vadimezan) has antiviral activity. Phase 3.

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Trivial name	ASA404, NSC 640488
Catalog Number	S1537
Molecular Formula	C16H8Cl4N2O2
CAS#	117570-53-3
Inchi	#N/A
Inchi Key	#N/A
SMILES	ClC1=CC(=C(OC2=CC=C(OC3=C(Cl)C=C(Cl)C=N3)C=C2)N=C1)Cl
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/DMXAA(ASA404).html
Additional Information	https://file.selleck.cn/downloads/struct/DMXAA-ASA404-chemical-structure-S1537.gif