Pralatrexate
Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines. Pralatrexate induces tumor cell apoptosis.
Trivial name | NSC 754230 |
Catalog Number | S1497 |
Molecular Formula | C19H12Cl2N4O3 |
CAS# | 146464-95-1 |
SMILES | CC1=C(C(=O)N(N1)C2=NC3=C(N2)C=CC(=C3Cl)Cl)C4C5=CC=CC=C5C(=O)O4 |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/Pralatrexate(Folotyn).html |
Additional Information | https://file.selleck.cn/downloads/struct/Pralatrexate-Folotyn-chemical-structure-S1497.gif |