Fludarabine
Fludarabine is a STAT1 activation inhibitor which causes a specific depletion of STAT1 protein (and mRNA) but not of other STATs. Also a DNA synthesis inhibitor in vascular smooth muscle cells. Fludarabine induces apoptosis.
| Trivial name | FaraA, Fludarabinum, NSC 118218 |
| Catalog Number | S1491 |
| Molecular Formula | C10H12FN5O4 |
| CAS# | 21679-14-1 |
| Inchi | InChI=1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/m1/s1 |
| Inchi Key | HBUBKKRHXORPQB-FJFJXFQQSA-N |
| SMILES | C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)F)N |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Fludarabine(Fludara).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Fludarabine-chemical-structure-s1491.gif |