Ispinesib (SB-715992)

Ispinesib (SB-715992, CK0238273) is a potent, specific and reversible inhibitor of kinesin spindle protein (KSP) with Ki app of 1.7 nM in a cell-free assay, no inhibition to CENP-E, RabK6, MCAK, MKLP1, KHC or Kif1A. Ispinesib induces mitotic arrest and apoptotic cell death.

Price Not Available 10mg Ispinesib (SB-715992) Supplier Page

Trivial name	CK0238273
Catalog Number	S1452
Molecular Formula	C30H33ClN4O2
CAS#	336113-53-2
Inchi	InChI=1S/C30H33ClN4O2/c1-20(2)27(34(17-7-16-32)29(36)23-12-10-21(3)11-13-23)28-33-26-18-24(31)14-15-25(26)30(37)35(28)19-22-8-5-4-6-9-22/h4-6,8-15,18,20,27H,7,16-17,19,32H2,1-3H3/t27-/m1/s1
Inchi Key	QJZRFPJCWMNVAV-HHHXNRCGSA-N
SMILES	CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C
Size	10mg
Supplier Page	http://www.selleckchem.com/products/Ispinesib-mesilate(SB-715992).html
Additional Information	https://file.selleck.cn/downloads/struct/Ispinesib-SB-715992-chemical-structure-S1452.gif