TCS7010 (Aurora A Inhibitor I)
TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B. Aurora A Inhibitor I (TC-S 7010) triggers apoptosis through the ROS-mediated UPR signaling pathway.
| Trivial name | TC-S 7010 |
| Catalog Number | S1451 |
| Molecular Formula | C25H20N2O2 |
| CAS# | 1158838-45-9 |
| Inchi | InChI=1S/C25H20N2O2/c1-29-25(28)17-12-10-16(11-13-17)24(20-14-26-22-8-4-2-6-18(20)22)21-15-27-23-9-5-3-7-19(21)23/h2-15,24,26-27H,1H3 |
| Inchi Key | BBAOKSZCULLDIW-UHFFFAOYSA-N |
| SMILES | COC(=O)C1=CC=C(C=C1)C(C2=CNC3=CC=CC=C32)C4=CNC5=CC=CC=C54 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Aurora-A-Inhibitor-I.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Aurora-A-Inhibitor-I-chemical-structure-S1451.gif |