Rolipram
The PDE4 selective inhibitor, Rolipram, inhibited immunopurified PDE4B and PDE4D activities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent.
| Trivial name | ZK-62711, SB 95952 |
| Catalog Number | S1430 |
| Molecular Formula | C18H18ClN5O3S |
| CAS# | 61413-54-5 |
| Inchi | InChI=1S/C18H18ClN5O3S/c19-13-5-7-16(20-11-13)21-18(28)22-17(25)12-4-6-14(15(10-12)24(26)27)23-8-2-1-3-9-23/h4-7,10-11H,1-3,8-9H2,(H2,20,21,22,25,28) |
| Inchi Key | AFOKREIUUQFDNW-UHFFFAOYSA-N |
| SMILES | C1CCN(CC1)C2=C(C=C(C=C2)C(=O)NC(=S)NC3=NC=C(C=C3)Cl)[N+](=O)[O-] |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Rolipram.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Rolipram-chemical-structure-S1430.gif |